Today, our PhD student Christina Anastasia Stamouli has “spikade” (nailed) her dissertation titled “Generation of Human Subtype-Specific Interneurons for Therapeutic Replacement and Disease Modelling” - a longstanding academic tradition in Sweden. This symbolic milestone typically takes place two to three weeks prior to the official thesis defence. Christina also carried out her Bachelor’s internship and completed her Master’s studies within our research group, making this an

We are pleased to share that our research has been featured in Vetenskap & Hälsa, a Swedish science communication platform. The article highlights our work on generating parvalbumin (PV) interneurons - cells that play a critical role in maintaining balance in brain activity and preventing excessive neuronal “noise.” We are excited to see our work communicated to a broader audience and to contribute to public engagement with neuroscience research.

We are proud to share that our research has been featured in a leading international biotechnology publication. The feature highlights our work on directly reprogramming glial cells into parvalbumin (PV) interneurons - an important neuronal subtype involved in maintaining brain circuit stability. This approach enables the generation of targeted neuronal subtypes without transitioning through a stem cell stage, offering new insights into cell identity and neural reprogramming.

SVT Vetenskap has highlighted exciting work from our group on how targeted brain cell replacement could open new therapeutic avenues for schizophrenia. The feature showcases our efforts to map affected cell types and explore how restoring them may help rebuild healthy neural circuits. 👉 Read the full article: https://www.svt.se/nyheter/vetenskap/sa-kan-hjarnceller-ersattas-for-att-behandla-schizofreni

We are happy to share a new article featuring Daniella Ottosson’s sabbatical experience in South Africa, highlighting her time at Stellenbosch University and STIAS. The piece captures how scientific collaboration, everyday life, and the unique local environment came together to inspire new ideas and perspectives for her neuroscience research. Read the full story here:🔗 https://www.intramed.lu.se/en/article/lund-south-africa-science-everyday-life-and-vineyards

We are excited to share our latest paper in Science Advances! In this study, we demonstrate direct lineage reprogramming of human glial cells into GABAergic interneurons using a three-dimensional (3D) culture system. Within just two weeks, single-nucleus RNA sequencing revealed distinct neuronal clusters, including a parvalbumin (PV) subtype with features of chandelier interneurons—a key player in cortical circuitry. Our trajectory analysis uncovered the stepwise conversion f

We are excited to announce that our latest paper is now published in Stem Cell Reports, where we present a 3D cell culture system...

A new video on Daniella Rylander Ottosson's research, published by the Knut and Alice Wallenberg Foundation

As we said goodbye to spring and welcomed the sunny days of summer, our lab crew got together for our favourite annual BBQ, and it was...

In this episode of MultiPark's podcast series, Emma Nyberg engages in a compelling conversation with Daniella Ottosson, delving into her...

Last week, our lab crew had our annual retreat, and it was a blast! We kicked things off with our usual team breakfast – the best way to...

Come join the Regenerative Neurophysiology Team! We are looking for a driven postdoctoral fellow to work on an exciting research project...

Dr. Andreas Bruzelius, the first PhD graduate from the Ottosson Lab, deserves hearty congratulations for his well-deserved doctoral...

Our first PhD student Andreas Bruzelius "nailed", or "spikade" as it is called in Swedish, his dissertation. This age-old tradition of...

In late June, as we embraced the arrival of summer and prepared for our well-deserved summer vacations, our lab group gathered for a...

The podcast covering the Lund Spring Symposium held from May 24-26th, featuring Dan Larhammar, Thoas Fioretos, and Sander van Deventer,...

ISCOMS is an annual congress held in the Netherlands that focuses on (bio)medical sciences and is organized by medical students. It is...

Join our team! We have an exciting job opportunity available for a research engineer specializing in electrophysiology at the esteemed...

The Lund Spring Symposium, held from May 24th to 26th, 2023, left a lasting impact on the field of molecular therapeutics. The presence...

This year's Neuroscience Day was held in Lund on 4th May and brought together researchers and students in the Öresund region and invited...